








Members of the lab attended this year’s ILC symposium in Leuven, Belgium.
Dr. Adrian Lee was recently interviewed for the “Do-Goodery Podcast: The Cancer Episode” to, as described by their website, “discuss what a jerk Cancer is. We Take Astro 101, learn about new weapons in the fight against Cancer, and how to support those who’ve received a Cancer diagnosis.”
Listen here:
Behold! The #Cancer Episode of The Do-Goodery Podcast!@PittTweet‘s Dr. Adrian Lee, a leading Cancer researcher, on the new weapons we have to fight it in this Golden Era of Cancer research.@OurClubhousePA on how to support those affected by Cancer.https://t.co/5OmJlL9ciw
— Rocco DeMaro (@RoccoDeMaro) November 12, 2018
We provide evidence that loss of E-cadherin hyperactivates the IGF1R pathway and increases sensitivity to IGF1R/InsR targeted therapy, thus identifying the IGF1R pathway as a potential novel target in E-cadherin–deficient breast cancers such as invasive lobular cancer.
Our latest paper focused on lobular breast cancer is now available. Role for SREBP1 and other regulators of fatty acid and cholesterol synthesis in invasive lobular breast cancer.