Several lab members volunteered at the Research tent at the annual Susan G. Komen “More Than Pink” walk in Pittsburgh. Adrian and Steffi were also interviewed by the local media.
Steffi Oesterreich and Lauren Brown were recently featured in the “Why We Ride” video for the UPMC Hillman Cancer Center Race to Crush Cancer ride.
Susan G. Komen features Dr. Adrian Lee: “‘We’ve Made Great Progress’: How Translational Research is Fueling Better Treatments for Patients through Precision Medicine”
Dr. Adrian Lee was recently interviewed for the “Do-Goodery Podcast: The Cancer Episode” to, as described by their website, “discuss what a jerk Cancer is. We Take Astro 101, learn about new weapons in the fight against Cancer, and how to support those who’ve received a Cancer diagnosis.”
Behold! The #Cancer Episode of The Do-Goodery Podcast!@PittTweet‘s Dr. Adrian Lee, a leading Cancer researcher, on the new weapons we have to fight it in this Golden Era of Cancer research.@OurClubhousePA on how to support those affected by Cancer.https://t.co/5OmJlL9ciw
— Rocco DeMaro (@RoccoDeMaro) November 12, 2018
New Publication! “Loss of E-cadherin Enhances IGF1–IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors”
Loss of E-cadherin Enhances IGF1–IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors
We provide evidence that loss of E-cadherin hyperactivates the IGF1R pathway and increases sensitivity to IGF1R/InsR targeted therapy, thus identifying the IGF1R pathway as a potential novel target in E-cadherin–deficient breast cancers such as invasive lobular cancer.
Thanks to Alan Faneca, David Decastro and other Pittsburgh Steelers for supporting research on metastatic breast cancer! Adrian and Steffi attended the Bid for Hope event, organized by Glimmer of Hope, on October 1st 2018 and were able to meet some of the players, talk about their research, and win a signed helmet! Go Steelers!
Drs. Adrian Lee and Steffi Oesterreich received the 2018 PNC Elsie Hillman Distinguished Scholar Award!
Congratulations to Drs. Adrian Lee and Steffi Oesterreich on receiving the 2018 PNC Elsie Hillman Distinguished Scholar Award. The award was announced at this year’s UPMC Hillman Gala that took place on Thursday, September 20 at PPG Paints Arena. Drs. Lee and Oesterreich were joined on that special evening by their daughters Paula and Nicola Lee-Oesterreich (photo below). You can read further coverage at the Pittsburgh-Post Gazette.
Photos from the gala:
New publication! “Comprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D cultures”!
Congratulation Dr. Nilgun Tasdemir and coauthors for their new publication generating an invaluable resource for lobular breast cancer research. Comprehensive characterization of ILC models.
New publication! “Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer”
Our latest paper focused on
lobular breast cancer is now available. Role for SREBP1 and other regulators of fatty acid and cholesterol synthesis in invasive lobular breast cancer.
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Our latest paper focused on lobular breast cancer is now available. Role for SREBP1 and other regulators of fatty acid and cholesterol synthesis in invasive lobular breast cancer. @tid1945 @kev_levine @nilguntasdemir_nt @steffioesterreich #breastcancer #breastcancerresearch #invasivelobularcarcinoma