








Members of the lab attended this year’s ILC symposium in Leuven, Belgium.
Another successful participation in the annual Susan G. Komen More Than Pink Walk is in the books! The lab also hosted a table for information on the “Hope for OTHERS” tissue donation program.
Several lab members volunteered at the Research tent at the annual Susan G. Komen “More Than Pink” walk in Pittsburgh. Adrian and Steffi were also interviewed by the local media.
The Lee/Oesterreich lab is delighted to receive two grant awards from the Breast Cancer Alliance (http://breastcanceralliance.org/).
The BCA selected to fund our projects entitled ‘Therapeutic targeting of novel pathways in breast cancer brain metastases’ and ‘Understanding the importance of ESR1 fusion genes in metastatic breast cancer”. The grants provide one year of funding support for these exciting projects.
We are very grateful for the funding to continue our quest to better understand and target endocrine resistant breast cancer.
We provide evidence that loss of E-cadherin hyperactivates the IGF1R pathway and increases sensitivity to IGF1R/InsR targeted therapy, thus identifying the IGF1R pathway as a potential novel target in E-cadherin–deficient breast cancers such as invasive lobular cancer.
Thanks to Alan Faneca, David Decastro and other Pittsburgh Steelers for supporting research on metastatic breast cancer! Adrian and Steffi attended the Bid for Hope event, organized by Glimmer of Hope, on October 1st 2018 and were able to meet some of the players, talk about their research, and win a signed helmet! Go Steelers!
Congratulations to Drs. Adrian Lee and Steffi Oesterreich on receiving the 2018 PNC Elsie Hillman Distinguished Scholar Award. The award was announced at this year’s UPMC Hillman Gala that took place on Thursday, September 20 at PPG Paints Arena. Drs. Lee and Oesterreich were joined on that special evening by their daughters Paula and Nicola Lee-Oesterreich (photo below). You can read further coverage at the Pittsburgh-Post Gazette.
Congratulation Dr. Nilgun Tasdemir and coauthors for their new publication generating an invaluable resource for lobular breast cancer research. Comprehensive characterization of ILC models.