Using natural language processing, we screened more than 2 million de-identified patients records at UPMC in order to identify rare metastases to the eye. We identified 28 patients with orbital metastases, with a significant enrichment in patients with ILC. There was a trend that these metastases were more frequently bilateral, but less frequently co-occurring with metastases to the brain in ILC compared to NST, suggesting different routes of spread but larger studies combining data from multiple centers are necessary to confirm these findings.
Important ILC Research: “Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology”
