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Important ILC Research: “Personalized Circulating Tumor DNA Testing for Detection of Progression and Treatment Response Monitoring in Patients With Metastatic Invasive Lobular Carcinoma of the Breast”

In a collaboration with Natera, we analyzed ctDNA longitudinally in 66 patients with  metastatic ILC using tumor-informed Signatera assays. Sequencing results from N=355 samples showed that ctDNA testing is a promising approach for surveillance and precision medicine in patients with metastatic ILC, a setting where imaging has often limited sensitivity.